[1]陳經緯,陳百計,勞偉思.廣州地區健康成年人血清鐵蛋白參考區間的建立[J].醫學信息,2019,(22):120-122.[doi:10.3969/j.issn.1006-1959.2019.22.039]
 CHEN Jing-wei,CHEN Bai-ji,LAO Wei-si.Establishment of Reference Interval of Serum Ferritin in Healthy Adults in Guangzhou Area[J].Medical Information,2019,(22):120-122.[doi:10.3969/j.issn.1006-1959.2019.22.039]
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廣州地區健康成年人血清鐵蛋白參考區間的建立()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2019年22期
頁碼:
120-122
欄目:
調查分析
出版日期:
2019-11-15

文章信息/Info

Title:
Establishment of Reference Interval of Serum Ferritin in Healthy Adults in Guangzhou Area
文章編號:
1006-1959(2019)22-0120-03
作者:
陳經緯陳百計勞偉思
(中山大學孫逸仙紀念醫院檢驗科,廣東 廣州 510120)
Author(s):
CHEN Jing-weiCHEN Bai-jiLAO Wei-si
(Department of Clinical Laboratory,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,Guangdong,China)
關鍵詞:
血清鐵蛋白膠乳免疫比濁法參考值范圍廣州地區
Keywords:
Serum ferritinLatex immunoturbidimetryReference rangeGuangzhou area
分類號:
R446.1
DOI:
10.3969/j.issn.1006-1959.2019.22.039
文獻標志碼:
A
摘要:
目的 了解廣州地區健康成人血清鐵蛋白水平,建立本地區血清鐵蛋白的正常參考值范圍。方法 收集中山大學孫逸仙紀念醫院2019年2月~9月參加體檢的健康成人286例,男132例、女154例,按照性別、年齡將受檢對象分為6組,分別為男、女青年組(18~39 歲),男、女中年組(40~59歲),男、女老年組(≥60 歲)。通過描繪血清鐵蛋白水平直方圖,應用Kolmogorov-Smirno方法進行正態性檢驗,對偏態分布的數據通過百分位數法求出雙側95%可信區間作為正常參考值范圍。結果 健康成人血清鐵蛋白水平呈偏態分布,男性和女性的正常參考值范圍分別為50.3~462.3 μg/L和4.5~358.6 μg/L;男性青年、中年、老年的正常參考值范圍分別為46.3~450.5 μg/L;56.5~441.3 μg/L;60.8~465.2 μg/L;女性青年、中年、老年的正常參考值范圍分別為3.5~209.4 μg/L;4.0~362.5 μg/L;21.0~383.8 μg/L。結論 廣州地區健康男性和女性血清鐵蛋白的正常參考值范圍存在較大差異,且與廠家說明書提供的參考值范圍差別較大,各地區、各實驗室有必要按性別、年齡建立適合本地區的血清鐵蛋白參考值范圍。
Abstract:
Objective To understand the serum ferritin levels of healthy adults in Guangzhou area and to establish a range of normal reference values for serum ferritin in this region. Methods The Sun Yat-sen Memorial Hospital of Sun Yat-Sen University collected 286 healthy adults from February to September 2019. There were 132 males and 154 females. The subjects were divided into 6 groups according to gender and age. They were male and female youth groups ( 18~39 years old), male and female middle-aged group (40~59 years old), male and female elderly group (≥60 years old). By depicting the histogram of serum ferritin levels, the Kolmogorov-Smirno method was used for the normality test, and the data of the skewed distribution was determined by the percentile method to obtain the two-sided 95% confidence interval as the normal reference range.Results Serum ferritin levels in healthy adults are skewed. The normal reference values for males and females are 50.3~462.3 μg/L and 4.5~358.6 μg/L, respectively. The normal reference values for male youth, middle age and old age are 46.3~450.5 μg/L; 56.5~441.3 μg/L; 60.8~465.2 μg/L; the normal reference range of female youth, middle age and old age is 3.5~209.4 μg/L; 4.0~362.5 μg/L; 21.0~ 383.8 μg/L.Conclusion There is a large difference in the range of normal reference values of healthy ferritin in healthy men and women in Guangzhou area, and there is a big difference between the reference range provided by the manufacturer's manual. It is necessary for each region and laboratories to establish a range of reference values for serum ferritin suitable for the area by gender and age.

參考文獻/References:

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更新日期/Last Update: 2019-11-15
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