[1]黃秋菊.胱抑素C及脂蛋白α在早期糖尿病腎病診斷中的價值研究[J].醫學信息,2018,(14):57-59.[doi:10.3969/j.issn.1006-1959.2018.14.018]
 HUANG Qiu-ju.The Value of Cystatin C and Lipoprotein α in the Diagnosis of Early Diabetic Nephropathy[J].Medical Information,2018,(14):57-59.[doi:10.3969/j.issn.1006-1959.2018.14.018]
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胱抑素C及脂蛋白α在早期糖尿病腎病診斷中的價值研究()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2018年14期
頁碼:
57-59
欄目:
論著
出版日期:
2018-07-15

文章信息/Info

Title:
The Value of Cystatin C and Lipoprotein α in the Diagnosis of Early Diabetic Nephropathy
文章編號:
1006-1959(2018)14-0057-03
作者:
黃秋菊
廣西柳州市人民醫院營養科,廣西 柳州 545006
Author(s):
HUANG Qiu-ju
Department of Nutrition,Liuzhou People’s Hospital,Liuzhou 545006,Guangxi,China
關鍵詞:
胱抑素C脂蛋白α糖尿病腎病尿微量白蛋白/尿肌酐
Keywords:
Key words:Cystatin CLipoprotein αDiabetic nephropathyUrinary microalbuminuria/urinary creatinine
分類號:
R587.1;R446.1
DOI:
10.3969/j.issn.1006-1959.2018.14.018
文獻標志碼:
A
摘要:
目的 探討胱抑素C及脂蛋白α在早期糖尿病腎病診斷中的應用價值。方法 選取2011年8月~2016年8月柳州市人民醫院收治的2型糖尿病患者125例為研究對象,根據尿微量白蛋白/尿肌酐的比值分為無DN組69例及早期DN組56例,兩組患者記錄年齡、身高、體重等,計算體重指數,Cys C通過快速免疫比濁法進行檢測,對比兩組Cys C、Lp(α)及其他相關指標之間的意義。結果 DN組Cys C(1.49±0.79)mg/L、Lp(α)(292.86±103.62)mg/L,高于無DN組(1.01±0.35)mg/L、(160.2±131.90)mg/L,差異有統計學意義(P<0.05),兩者是DN發生的獨立危險因素。結論 Cys C、Lp(α)與DN的發生發展有相關性,兩者聯合檢測對早期診斷DN有實用價值。
Abstract:
Abstract:Objective To evaluate the value of cystatin C and lipoprotein α in the diagnosis of early diabetic nephropathy.Methods 125 cases of type 2 diabetes patients admitted to Liuzhou People's Hospital from August 2011 to August 2016 were selected as subjects.According to the ratio of urinary microalbuminuria/urinary creatinine,69 cases were in the non-DN group and 56 cases in the early DN group.The age,height,and weight of the two groups were recorded.Body mass index was calculated.Cys C was detected by rapid immunoturbidimetry,and the significance between Cys C,Lp(α)and other related indicators was compared.Results Cys C(1.49±0.79)mg/L、Lp(α)(292.86±103.62)mg/L in DN group was significantly higher than that in non-DN group(1.01±0.35)mg/L、(160.2±131.90)mg/L,and the difference was statistically significant(P<0.05).Both were independent risk factors of DN.Conclusion There is a correlation between Cys,LP(α)and the occurrence and development of DN.The combined detection of Cys,LP(α)is of practical value in the early diagnosis of DN.

參考文獻/References:

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更新日期/Last Update: 2018-07-15
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