[1]麥穎達,許衛華,李 峰,等.慢性鼻竇炎伴鼻息肉炎癥因子的研究[J].醫學信息,2020,(04):40-43.[doi:10.3969/j.issn.1006-1959.2020.04.013]
 MAI Ying-da,XU Wei-hua,LI Feng,et al.Study on Inflammatory Factors of Chronic Rhinosinusitis with Nasal Polyps[J].Medical Information,2020,(04):40-43.[doi:10.3969/j.issn.1006-1959.2020.04.013]
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慢性鼻竇炎伴鼻息肉炎癥因子的研究()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2020年04期
頁碼:
40-43
欄目:
綜述
出版日期:
2020-02-15

文章信息/Info

Title:
Study on Inflammatory Factors of Chronic Rhinosinusitis with Nasal Polyps
文章編號:
1006-1959(2020)04-0040-04
作者:
麥穎達許衛華李 峰
(1.廣東省湛江市廣東醫科大學,廣東 湛江 524000;2.廣東省湛江市廣東醫科大學附屬醫院耳鼻咽喉科,廣東 湛江 524000)
Author(s):
MAI Ying-daXU Wei-huaLI Fenget al
(1.Guangdong Medical University,Zhanjiang 524000,Guangdong,China;2.Department of Otolaryngology,the Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,Guangdong,China)
關鍵詞:
慢性鼻竇炎伴鼻息肉炎癥因子鼻竇炎白介素單克隆抗體
Keywords:
Chronic rhinosinusitis with nasal polypsInflammatory factorsNasosinusitisInterleukinMonoclonal antibody
分類號:
R765
DOI:
10.3969/j.issn.1006-1959.2020.04.013
文獻標志碼:
A
摘要:
慢性鼻竇炎伴鼻息肉(CRSwNP)是一種異質性的鼻腔炎及鼻竇黏膜慢性炎癥引起的疾病,其中引起炎癥的因子及其發生機制復雜,根據鼻竇黏膜組織嗜酸性粒細胞增多的嚴重程度大致可分為嗜酸粒細胞性鼻息肉和非嗜酸粒細胞性鼻息肉,兩者的炎癥因子機制和治療預后存在明顯的差異。本文基于國內外對CRSwNP潛在的相關炎癥因子的研究成果,總結了兩類主要影響CRSwNP的潛在相關異質性炎癥因子及其現有的相關靶點治療藥物,以期為此類疾病的研究工作提供參考。
Abstract:
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a disease caused by heterogeneous rhinitis and chronic inflammation of the sinus mucosa. The factors that cause inflammation are complicated and their mechanisms are complex. Severity can be roughly divided into eosinophilic nasal polyps and non-eosinophilic nasal polyps. There is a significant difference in the mechanisms of inflammatory factors and prognosis of the two. Based on the research results of CRSwNP potential related inflammatory factors at home and abroad, this paper summarizes two types of potentially related heterogeneous inflammatory factors that mainly affect CRSwNP and their existing related target therapeutic drugs, with a view to providing research work for such diseases reference.

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