[1]范均熔,王慶東,曾凡榮.瑞芬太尼復合丙泊酚麻醉在腹腔鏡遠端胃癌D2根治術中的應用[J].醫學信息,2020,(04):136-138.[doi:10.3969/j.issn.1006-1959.2020.04.043]
 FAN Jun-rong,WANG Qing-dong,ZENG Fan-rong.Application of Remifentanil and Propofol Anesthesia in Laparoscopic DistalGastric Cancer D2 Radical Operation[J].Medical Information,2020,(04):136-138.[doi:10.3969/j.issn.1006-1959.2020.04.043]
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瑞芬太尼復合丙泊酚麻醉在腹腔鏡遠端胃癌D2根治術中的應用()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2020年04期
頁碼:
136-138
欄目:
藥物與臨床
出版日期:
2020-02-15

文章信息/Info

Title:
Application of Remifentanil and Propofol Anesthesia in Laparoscopic DistalGastric Cancer D2 Radical Operation
文章編號:
1006-1959(2020)04-0136-03
作者:
范均熔王慶東曾凡榮
(佳木斯大學附屬第一醫院麻醉科,黑龍江 佳木斯 154000)
Author(s):
FAN Jun-rongWANG Qing-dongZENG Fan-rong
(Department of Anesthesiology,the First Affiliated Hospital of Jiamusi University,Jiamusi 154000,Heilongjiang,China)
關鍵詞:
瑞芬太尼丙泊酚D2根治術麻醉質量
Keywords:
RemifentanilFentanylD2 radical operationQuality of anaesthsia
分類號:
R614;R735.2
DOI:
10.3969/j.issn.1006-1959.2020.04.043
文獻標志碼:
A
摘要:
目的 探討瑞芬太尼復合丙泊酚麻醉在腹腔鏡遠端胃癌D2根治術中的應用效果。方法 選取2017年10月1日~2019年10月1日我院收治的行腹腔鏡遠端胃癌D2根治術的進展期胃癌患者96例,采用隨機數字表法分為觀察組和對照組,每組48例,觀察組采用瑞芬太尼復合丙泊酚麻醉,對照組采用芬太尼復合丙泊酚麻醉,比較兩組麻醉效果,麻醉前(T0)、麻醉中(T1)、手術完畢時(T2)時心率(HR)、平均動脈壓(MAP)、氧飽和度(SpO2)、皮質醇(COR)、白細胞介素-6(IL-6)、葡萄糖(GLU)及不良反應發生情況。結果 觀察組麻醉總有效率為95.83%,高于對照組的75.00%,差異具有統計學意義(P<0.05);觀察組T1、T2時間點HR低于對照組,MAP、SpO2高于對照組,差異具有統計學意義(P<0.05);觀察組T1、T2時皮質COR、IL-6、GLU水平低于對照組,差異具有統計學意義(P<0.05);觀察組麻醉后不良反應發生率為8.33%,低于對照組的22.92%,差異具有統計學意義(P<0.05)。結論 瑞芬太尼復合丙泊酚麻醉在腹腔鏡遠端胃癌D2根治術中的應用效果良好,對患者血流動力學影響較小,患者生命體征平穩,且不良反應發生率較低。
Abstract:
Objective To investigate the effect of remifentanil combined with propofol anesthesia in laparoscopic distal gastric cancer D2 radical operation.Methods 96 patients with advanced gastric cancer who underwent laparoscopic distal gastric cancer D2 radical surgery who were treated in our hospital from October 1,2017 to October 1,2019 were divided into observation group and control group by random number table method,For each group of 48 patients,the observation group was anesthetized with remifentanil and propofol,and the control group was anesthetized with fentanyl and propofol.Compare the effects of anesthesia between two groups,before anesthesia (T0),during anesthesia(T1),at the completion of surgery(T2),heart rate(HR),mean arterial pressure (MAP),oxygen saturation(SpO2),cortisol(COR),Interleukin-6(IL-6),glucose(GLU)and incidence of adverse reactions.Results The total effective rate of anesthesia in the observation group was 95.83%, which was higher than 75.00% in the control group,the difference was statistically significant(P<0.05).The HR at time points T1 and T2 in the observation group was lower than that in the control group,and MAP and SpO2 were higher than those in the control group,the difference was statistically significant(P<0.05).The levels of COR, IL-6, and GLU in the observation group at T1 and T2 were lower than those in the control group,the differences were statistically significant(P<0.05);the incidence of adverse reactions after anesthesia in the observation group was 8.33%,which was lower than that of 22.92% in the control group,the difference was statistically significant(P<0.05).Conclusion Remifentanil combined with propofol anesthesia has a good effect in laparoscopic distal gastric cancer D2 radical surgery,with less effect on hemodynamics,stable vital signs,and fewer adverse reactions.

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