[1]于 波.靜脈注射丙種球蛋白治療早產兒肺炎臨床療效[J].醫學信息,2020,(04):149-150.[doi:10.3969/j.issn.1006-1959.2020.04.048]
 YU Bo.Clinical Efficacy of Intravenous Gamma Globulin in Premature Infants with Pneumonia[J].Medical Information,2020,(04):149-150.[doi:10.3969/j.issn.1006-1959.2020.04.048]
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靜脈注射丙種球蛋白治療早產兒肺炎臨床療效()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2020年04期
頁碼:
149-150
欄目:
藥物與臨床
出版日期:
2020-02-15

文章信息/Info

Title:
Clinical Efficacy of Intravenous Gamma Globulin in Premature Infants with Pneumonia
文章編號:
1006-1959(2020)04-0149-02
作者:
于 波
(佳木斯市中心醫院新生兒科,黑龍江 佳木斯 154002)
Author(s):
YU Bo
(Department of Neonatal,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
關鍵詞:
靜脈注射丙種球蛋白早產兒肺炎
Keywords:
Intravenous gamma globulinPremature infantsPneumonia
分類號:
R722.6
DOI:
10.3969/j.issn.1006-1959.2020.04.048
文獻標志碼:
A
摘要:
目的 分析靜脈注射丙種球蛋白治療早產兒肺炎臨床療效。方法 選取2018年2月~2019年2月在我院治療的早產兒肺炎54例,采用隨機數字表法分為對照組和觀察組,各27例。對照組采用常規治療,觀察組在對照組基礎上給予靜脈注射丙種球蛋白治療,比較兩組臨床治療總有效率、臨床體征(體溫恢復、呼吸頻率正常、青紫緩解、啰音消失)改善時間、治療前后血清免疫球蛋白G(IgG)水平以及臨床并發癥發生情況。結果 觀察組臨床治療總有效率為92.59%,高于對照組的81.48%(P<0.05);觀察組體溫恢復、呼吸頻率正常、青紫緩解、啰音消失時間均短于對照組(P<0.05);治療后兩組IgG水平均高于治療前,且觀察組高于對照組(P<0.05);觀察組并發癥發生率為11.11%,低于對照組的25.92%(P<0.05)。結論 靜脈注射丙種球蛋白治療早產兒肺炎臨床療效確切,有助于改善早產兒血清lgG水平,緩解臨床癥狀,降低并發癥發生率。
Abstract:
Objective To analyze the clinical efficacy of intravenous gamma globulin in the treatment of premature infants with pneumonia.Methods 54 cases of pneumonia of premature infants treated in our hospital from February 2018 to February 2019 were selected and divided into a control group and an observation group with a random number table method, with 27 cases in each group. The control group received conventional treatment, and the observation group received intravenous gamma globulin therapy on the basis of the control group. The total effective rate of clinical treatment, recovery of clinical signs (temperature recovery, normal breathing rate, bluish cyanosis, disappearance of snoring sounds), serum immunoglobulin G (IgG) levels before and after treatment, and clinical complications were compared between the two groups.Results The total effective rate of clinical treatment in the observation group was 92.59%, which was higher than 81.48% in the control group(P<0.05). The time of body temperature recovery, normal breathing rate, bluish remission, and snoring disappearance in the observation group were shorter than those in the control group(P<0.05); the IgG levels of the two groups after treatment were higher than before the treatment, and the observation group was higher than the control group(P<0.05); the incidence of complications in the observation group was 11.11%, which was lower than 25.92% of the control group(P<0.05).Conclusion Intravenous injection of gamma globulin is effective in the treatment of pneumonia in preterm infants, and it is helpful to improve serum lgG levels in preterm infants, relieve clinical symptoms, and reduce the incidence of complications.

參考文獻/References:

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更新日期/Last Update: 2020-02-15
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