[1]周雯雯.磷酸肌酸治療兒童肺炎伴心肌損害的效果[J].醫學信息,2020,(04):155-157.[doi:10.3969/j.issn.1006-1959.2020.04.051]
 ZHOU Wen-wen.Effect of Creatine Phosphate on Children with Pneumonia and Myocardial Damage[J].Medical Information,2020,(04):155-157.[doi:10.3969/j.issn.1006-1959.2020.04.051]
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磷酸肌酸治療兒童肺炎伴心肌損害的效果()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2020年04期
頁碼:
155-157
欄目:
藥物與臨床
出版日期:
2020-02-15

文章信息/Info

Title:
Effect of Creatine Phosphate on Children with Pneumonia and Myocardial Damage
文章編號:
1006-1959(2020)04-0155-03
作者:
周雯雯
(佳木斯市中心醫院兒科,黑龍江 佳木斯 154002)
Author(s):
ZHOU Wen-wen
(Department of Pediatrics,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
關鍵詞:
兒童肺炎心肌損害磷酸肌酸
Keywords:
Childhood pneumoniaMyocardial damageCreatine phosphate
分類號:
R725.6
DOI:
10.3969/j.issn.1006-1959.2020.04.051
文獻標志碼:
A
摘要:
目的 觀察采用磷酸肌酸治療兒童肺炎伴心肌損害的臨床效果。方法 選擇2018年1月~2019年5月我院治療的兒童肺炎伴心肌損害患兒96例,采用隨機數字表法分為對照組和觀察組,各48例。對照組給予常規抗感染和對癥治療,觀察組在對照組基礎上給予磷酸肌酸治療,比較兩組臨床治療總有效率、臨床癥狀(退熱、咳嗽、咳痰、氣促、肺部啰音)改善時間、心肌酶指標[磷酸肌酸激酶(CK)、天冬氨酸轉氨酶(AST)、同工酶(CK-MB)、乳酸脫氫(LDH)]及不良反應發生情況。結果 觀察組治療總有效率為91.67%,高于對照組的81.25%,差異有統計學意義(P<0.05);觀察組退熱、咳嗽、咳痰、氣促、肺部啰音改善時間均短于對照組,差異有統計學意義(P<0.05);治療后兩組CK、AST、CK-MB、LDH均低于治療前,且觀察組低于對照組,差異有統計學意義(P<0.05);兩組均未發生嚴重不良反應。結論 兒童肺炎伴心肌損害采用磷酸肌酸治療療效確切,有助于改善臨床癥狀及心肌酶指標,促進患兒的康復。
Abstract:
Objective To observe the clinical effect of creatine phosphate treatment in children with pneumonia and myocardial damage.Methods 96 children with pneumonia and myocardial damage treated in our hospital from January 2018 to May 2019 were selected and randomly divided into a control group and an observation group, with 48 cases in each group. The control group was given conventional anti-infective and symptomatic treatment, and the observation group was given creatine phosphate treatment on the basis of the control group. The total effective rate and clinical symptoms of the two groups were compared (antipyretics, cough, sputum, shortness of breath, lung murmur) improvement time, myocardial enzyme index [phosphocreatine kinase (CK), aspartate aminotransferase (AST), isoenzyme (CK-MB), lactate dehydrogenation (LDH)] and adverse reactions. Results The total effective rate of treatment in the observation group was 91.67%, which was higher than the control group’s 81.25%,the difference was statistically significant (P<0.05). The improvement time of fever, cough, sputum, shortness of breath, and lung snoring in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).After treatment, CK, AST, CK-MB, and LDH in the two groups were lower than before treatment, and the observation group was lower than the control group, the difference was statistically significant(P<0.05);no serious adverse reactions occurred in both groups.Conclusion The use of creatine phosphate in children with pneumonia and myocardial damage is effective, which can help improve clinical symptoms and myocardial enzymes and promote the rehabilitation of children.

參考文獻/References:

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更新日期/Last Update: 2020-02-15
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