[1]鄭 新,張 穎.血清TNF-α、IL-6、IL-8水平對ARDS患者病情的預測價值[J].醫學信息,2020,(04):177-178.[doi:10.3969/j.issn.1006-1959.2020.04.060]
 ZHENG Xin,ZHANG Ying.Predictive Value of Serum TNF-α,IL-6 and IL-8 Levels in Patients with ARDS[J].Medical Information,2020,(04):177-178.[doi:10.3969/j.issn.1006-1959.2020.04.060]
點擊復制

血清TNF-α、IL-6、IL-8水平對ARDS患者病情的預測價值()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2020年04期
頁碼:
177-178
欄目:
診療技術
出版日期:
2020-02-15

文章信息/Info

Title:
Predictive Value of Serum TNF-α,IL-6 and IL-8 Levels in Patients with ARDS
文章編號:
1006-1959(2020)04-0177-02
作者:
鄭 新張 穎
(佳木斯市中心醫院急診科1,心內一科2,黑龍江 佳木斯 154003)
Author(s):
ZHENG XinZHANG Ying
(Department of Emergency1,Department of Cardiology,Subject One2,Jiamusi Central Hospital,Jiamusi 154003,Heilongjiang,China)
關鍵詞:
急性呼吸窘迫綜合征腫瘤壞死因子-α白細胞介素-6白細胞介素-8
Keywords:
Acute respiratory distress syndromeTumor necrosis factor-αInterleukin-6Interleukin-8
分類號:
R563.8
DOI:
10.3969/j.issn.1006-1959.2020.04.060
文獻標志碼:
A
摘要:
目的 探究血清腫瘤壞死因子-α(TNF-α)、白細胞介素-6(IL-6)、白細胞介素-8(IL-8)水平在急性呼吸窘迫綜合征(ARDS)預測中的價值。方法 回顧性分析2018年1月~2019年8月我院收治的67例ARDS患者臨床資料,根據病情嚴重程度將其分為輕度組(21例)、中度組(22例)、重度組(24例),比較三組血清TNF-α、IL-6、IL-8水平,并用ROC曲線評價其對ARDS患者病情的預測價值。結果 重度組血清TNF-α、IL-6、IL-8水平高于中度組、輕度組,中度組血清TNF-α、IL-6、IL-8水平高于輕度組,差異有統計學意義(P<0.05);血清TNF-α、IL-6、IL-8聯合檢測敏感度與特異度高于TNF-α、IL-6、IL-8單一檢測。結論 血清TNF-α、IL-6、IL-8水平均可早期預測ARDS病情進展,其聯合檢測敏感度與特異度均較高,效果更為理想。
Abstract:
Objective To investigate the application of serum tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-8 (IL-8) levels in the prediction and evaluation of acute respiratory distress syndrome (ARDS) value. Methods The clinical data of 67 patients with ARDS treated in our hospital from January 2018 to August 2019 were retrospectively analyzed. They were divided into mild group (21 cases), moderate group (22 cases), and severe group (24 cases),according to the severity of the disease,the serum levels of TNF-α, IL-6 and IL-8 were compared between the three groups, and their predictive value for the condition of ARDS patients was evaluated by using the ROC curve. Results Serum levels of TNF-α, IL-6, and IL-8 in the severe group were higher than those in the moderate and mild groups, and the serum levels of TNF-α, IL-6, and IL-8 in the moderate group were higher than those in the mild group,the difference was statistically significant (P<0.05);The sensitivity and specificity of combined detection of TNF-α, IL-6 and IL-8 were higher than that of single detection.Conclusion Serum levels of TNF-α, IL-6, and IL-8 can all predict the progression of ARDS at an early stage, and the combined detection sensitivity and specificity are higher, and the effect is more ideal.

參考文獻/References:

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更新日期/Last Update: 2020-02-15
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